Cannabinol (CBN) is one of over 100 cannabinoids naturally found within the Cannabis plant. CBN is a rare cannabinoid produced at low levels within the cannabis plant and is uniquely derived from the breakdown of tetrahydrocannabinol (THC). CBN and its precursor cannabinolic acid (CBNA) help regulate sleep and mitigate pain, inflammation, and neurological, digestive and skin conditions.


The potent antioxidant properties of CBN facilitate several health-promoting effects.

Promotes pain relief

CBN/CBNA has been extensively studied by the pharmaceutical industry for its pain-relieving effects. By increasing the threshold at which pain is felt, CBN can promote analgesia.

Supports the immune system

Oxidative stress can disrupt the immune system and cause the immune system to overreact against the body. By neutralizing oxidative stress, CBN can support healthy immune function and promote defense against autoimmune conditions

Protects the brain

The effects of CBN/CBNA on the brain and nervous system have also been investigated for its potential in neurological conditions. By protecting the brain from oxidative stress, CBN can promote movement in conditions like amyotrophic lateral sclerosis (ALS)

Defends the skin

CBN has been harnessed within dermatology and cosmetology. By decreasing levels of inflammatory molecules, such as tumor necrosis factor (TNF) and interleukins, CBN/CBNA can help promote a healthy inflammatory response in conditions, such as dermatitis, acne, and skin cancer.

Promotes optimal digestion

CBN targets the endocannabinoid system, which links various parts of the body, such as the brain and gastrointestinal (GI) tract. Overactivation of the GI tract can worsen conditions, such as Crohn’s disease and Ulcerative Colitis. By regulating digestion, CBN can help prevent overactivation of the GI tract

Due to these numerous health benefits, the food industry has also taken advantage of THCA. Cannabis tea has become increasingly popular with THCA being one of the most abundant cannabinoids present within the Cannabis plant.

Advantages of Biosynthetic CBN/CBNA

Rare cannabinoids, such as CBN/CBNA, exist in minimal quantities in cannabis plants. This makes their extraction and purification inefficient, costly and environmentally taxing. CBN/CBNA are extracted from cannabis, which requires significant regulatory oversight and can produce inconsistent yields prone to contamination from pests, mold, and pesticides. Due to these limitations, the chemical synthesis of CBN has become the leading production method.

However, chemical synthesis produces artificial forms of CBN, which can have undesirable side effects.

To overcome these challenges, the production of CBN/CBNA through biosynthesis has become more popular. This process offers a way to reduce the environmental footprint, decrease the time of production, circumvent regulatory oversight, and produce high-quality cannabinoids. Biosynthesis, a process that has been used for several years in multiple industries, revolutionizes the production of cannabinoids by reducing the cost of their production by 70-90%.

Biomedican uses a unique proprietary yeast to produce CBN/CBNA that is identical to its counterparts in nature. The advantage of this natural process is that it is 100% pure, reliable, and does not come with the undesirable side effects of chemical synthesis.