Overview

Tetrahydrocannabivarin (THCV) is one of the 113 cannabinoids found within the cannabis plant and is an analog to its well-known counterpart, tetrahydrocannabinol (THC). THCV and its precursor tetrahydrocannabivarin acid (THCVA) reduce appetite, assist sugar metabolism, have neuroprotective properties, and stimulate the body’s ability to grow bone.

Benefits 

THCV targets the endocannabinoid system to promote health and wellness

Supports digestion and weight loss

As a cannabinoid, THCV targets the endocannabinoid system, which is linked to hunger and satiety. By regulating receptors in the gastrointestinal (GI) tract, THCV can
  • Promote the balance of food intake and aid in weight loss.
  • Promote optimal sensitivity to insulin, sugar metabolism, and energy usage.
  • Defend against chemotherapy-induced nausea and vomiting by regulating the body’s GI reaction to chemical particles
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Protects the brain

THCV is well-known for its neuroprotective effects on the brain, and can

  • Promote the activation of a major mood hormone called serotonin, which can defend against the excess movement seen in conditions like schizophrenia and Parkinson’s disease.
  • Support the balance of ions in the brain and promote suppression of seizure activity in epilepsy.
  • Defend against addiction behavior, through the anti-nicotine properties of THCV.
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Promotes skin and bone health

A therapeutic avenue that has been of interest to the cosmetic and orthopedic pharmaceutical industries is the effect of THCV on musculoskeletal wellness and remodeling. This is because THCV can support the stimulation of bone marrow cells and the synthesis of bone.

These promising effects of THCV/THCVA have spurred interest by the nutraceutical, cosmetic, and pharmaceutical industries for use in various applications.

Advantages of Biosynthetic THCV/THCVA

Rare cannabinoids, such as THCV/THCVA, exist in minimal quantities in cannabis plants. Therefore, their extraction and purification can be inefficient, costly and environmentally taxing. THCV/THCVA are extracted from cannabis, which requires significant regulatory oversight and can produce inconsistent yields prone to contamination from pests, mold, and pesticides. As a result, the chemical synthesis of THCV/THCVA has become the leading production method.

However, chemical synthesis produces artificial forms of THCV/THCVA, which can have undesirable side effects.

The production of THCV/THCVA through biosynthesis, on the other hand, offers a way to reduce the environmental footprint, decrease the time of production, circumvent regulatory oversight, and produce high-quality cannabinoids. Biosynthesis, a process that has been used for several years in multiple industries, revolutionizes the production of cannabinoids by reducing the cost of their production by 70-90%.

Biomedican uses a unique proprietary yeast, which undergoes the natural metabolic process of fermentation, to produce THCV/THCVA that is identical to its counterparts in nature. The advantage of this natural process is that it is 100% pure, reliable, and does not come with the undesirable side effects of chemical synthesis.